2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester

Molecular Formula: C 21 H 17 ClN 2 O 3

Molecular Weight: 380.82

CAS Number: 62669-70-9

Descriptions:

Application: Useful as a laser dye and to have selective cell growth effects.

Biochem/physiol Actions: Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of MRP1.

Safety Statements: 22-24/25