Sigma C6762 细胞松弛素B Cytochalasin B
产品详细说明:
Cytochalasin B from Drechslera dematioidea ≥ 98% (HPLC), powder
Synonym Phomin
Molecular Formula C 29 H 37 NO 5
Molecular Weight 479.61
CAS Number 14930-96-2
Biochem/physiol Actions One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,and in studies on cytokinesis. 1 Probe for the two hexose-transport systems in rat L6 myoblasts. 2
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
Properties
assay ………………………………………………………. ≥ 98% (HPLC)
form …………………………………………………………powder
color……………………………………………………….. white
solubility ………………………………………………….ethanol: 20 mg/mL
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